The newly-announced run is six dates from August 5 in Syracuse, New York, to Aug. 18 in El Paso, Texas.
Crüe and Def Leppard are scheduled to play a two-night residency in Atlantic City, NJ, February 10 and 11, before heading out for a run of dates in Latin America and Europe, that will keep them busy through early-July.
Tickets for the U.S. shows go on sale to the general public December 16.
The 2023 tour will be Mötley Crüe's first-ever without cofounding guitarist Mick Mars, who confirmed in October that he is retiring from touring after decades of battling a painful arthritic condition called Ankylosing Spondylitis on the road.
Mötley Crüe's longtime friend and collaborator guitarist John 5 is joining the band in a touring capacity to fill in for Mars.
"We will carry out Mick's wish and continue to tour the world as planned in 2023," the band wrote. "No doubt will it take an absolutely outstanding musician to fill Mick's shoes so we are grateful that our good friend John 5 has agreed to come on board and join us moving forward."